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Premixed Packets of USP Grade Sodium Chloride & Sodium Bicarbonate (Purity level 99% or higher) The NeilMed Sinus Rinse system is a large volume nasal rinse that will deliver 120mL to 240mL(8 fl oz) of saline solution into the nasal passages. Adding one blue packet of NeilMed SINUS RINSE™ to 240mL(8 fl oz) of water will make an Isotonic saline solution (Hypertonic with 2 or more packets) that is pH balanced and preservative free.